Edward Ziff received a bachelor’s degree in Chemistry from Columbia University and a Ph.D. from Princeton University in Biochemistry. As a postdoctoral student in Cambridge, he conducted early genome sequencing studies in the laboratory of Fred Sanger. Ed later served on the faculties of the Imperial Cancer Research Fund in London and Rockefeller University in New York studying mechanisms of oncogenesis and transcriptional regulation. He next joined the faculty of New York University School of Medicine, where he is now Professor of Biochemistry and Molecular Pharmacology and Neural Science and was an Investigator of the Howard Hughes Medical Institute. Ed researches brain function and neurological disease, in particular mechanisms of synaptic plasticity and neuronal homeostasis and regulation by reward. He has written on science topics for the lay public and also coauthored a popular book on DNA.